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1

Cell Growth Inhibitory Effect of Cinnamic Acid Derivatives from Propolis on Human Tumor Cell Lines

Akao, Yukihiro, Maruyama, Hiroe, Matsumoto, Kenji, Ohguchi, Kenji, Nishizawa, Kumi, Sakamoto, Takashi, Araki, Yoko, Mishima, Satoshi, Nozawa, Yoshinori

Journal:

Biological & Pharmaceutical Bulletin

Year:

2003

Language:

english

File:

PDF, 106 KB

english, 2003

2

Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation

Tomohiro Itoh, Kenji Ohguchi, Munekazu Iinuma, Yoshinori Nozawa, Yukihiro Akao

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

3

Inhibitory effects of flavonoid glycosides isolated from the peel of Japanese persimmon (Diospyros kaki Fuyu) on antigen-stimulated degranulation in rat basophilic leukaemia RBL-2H3 cells

Tomohiro Itoh, Kenji Ohguchi, Chizuru Nakajima, Masayoshi Oyama, Munekazu Iinuma, Yoshinori Nozawa, Yukihiro Akao, Masafumi Ito

Journal:

Year:

2011

Language:

english

File:

PDF, 754 KB

english, 2011

4

Inhibitory Effects of Flavonoid Glycosides Isolated from the Peel of Japanese Persimmon (Diospyros kaki ‘Fuyu’) on Melanin Biosynthesis

Ohguchi, Kenji, Nakajima, Chizuru, Oyama, Masayoshi, Iinuma, Munekazu, Itoh, Tomohiro, Akao, Yukihiro, Nozawa, Yoshinori, Ito, Masafumi

Journal:

Biological & Pharmaceutical Bulletin

Year:

2010

Language:

english

File:

PDF, 136 KB

english, 2010

5

Mechanism of increased PLD1 gene expression during early adipocyte differentiation process of mouse cell line 3T3-L1

Siqiang Gao, Hiromi Ito, Masashi Murakami, Kayo Yoshida, Yoko Tagawa, Kazumi Hagiwara, Akira Takagi, Tetsuhito Kojima, Motoshi Suzuki, Yoshiko Banno, Kenji Ohguchi, Yoshinori Nozawa, Takashi Murate

Journal:

Journal of Cellular Biochemistry

Year:

2010

Language:

english

File:

PDF, 295 KB

english, 2010

6

Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells

Kenji Ohguchi, Yoshiko Banno, Yoshihito Nakagawa, Yukihiro Akao, Yoshinori Nozawa

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 383 KB

english, 2005

7

Preferential target is mitochondria in α-mangostin-induced apoptosis in human leukemia HL60 cells

Kenji Matsumoto, Yukihiro Akao, Hong Yi, Kenji Ohguchi, Tetsuro Ito, Toshiyuki Tanaka, Emi Kobayashi, Munekazu Iinuma, Yoshinori Nozawa

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 709 KB

english, 2004

8

Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells

Kenji Matsumoto, Yukihiro Akao, Kenji Ohguchi, Tetsuro Ito, Toshiyuki Tanaka, Munekazu Iinuma, Yoshinori Nozawa

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 250 KB

english, 2005

9

Mechanism of the melanogenesis stimulation activity of (−)-cubebin in murine B16 melanoma cells

Noriko Hirata, Shunsuke Naruto, Kenji Ohguchi, Yukihiro Akao, Yoshinori Nozawa, Munekazu Iinuma, Hideaki Matsuda

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 197 KB

english, 2007

10

Eupalinin A isolated from Eupatorium chinense L. induces autophagocytosis in human leukemia HL60 cells

Tomohiro Itoh, Yuko Ito, Kenji Ohguchi, Masayoshi Ohyama, Munekazu Iinuma, Yoshinori Otsuki, Yoshinori Nozawa, Yukihiro Akao

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.39 MB

english, 2008

11

Interactive effects of polymethoxy flavones from Citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells

Yukihiro Akao, Tomohiro itoh, Kenji Ohguchi, Munekazu Iinuma, Yoshinori Nozawa

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 846 KB

english, 2008

12

Inhibitory effects of polymethoxy flavones isolated from Citrus reticulate on degranulation in rat basophilic leukemia RBL-2H3: Enhanced inhibition by their combination

Tomohiro Itoh, Kenji Ohguchi, Munekazu Iinuma, Yoshinori Nozawa, Yukihiro Akao

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

13

Changes in the Activity and mRNA Levels of Phospholipase D During Ceramide-Induced Apoptosis in Rat C6 Glial Cells

Shin-ichi Yoshimura, Hideki Sakai, Kenji Ohguchi, Shigeru Nakashima, Yoshiko Banno, Yasuaki Nishimura, Noboru Sakai, Yoshinori Nozawa

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.19 MB

english, 1997

14

Involvement of calpain in melanogenesis of mouse B16 melanoma cells

Kenji Ohguchi, Yukihiro Akao, Yoshinori Nozawa

Journal:

Molecular and Cellular Biochemistry

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

15

Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway

Yoshiko Banno, Satoshi Nemoto, Masashi Murakami, Masashi Kimura, Yoshihito Ueno, Kenji Ohguchi, Akira Hara, Yukio Okano, Yukio Kitade, Minoru Onozuka, Takashi Murate, Yoshinori Nozawa

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

16

Abnormal Expression of the Novel Epidermal Enzyme, Glucosylceramide Deacylase, and the Accumulation of its Enzymatic Reaction Product, Glucosylsphingosine, in the Skin of Patients with Atopic Dermatitis

Ishibashi, Mutsumi, Arikawa, Junko, Okamoto, Reiko, Kawashima, Makoto, Takagi, Yutaka, Ohguchi, Kenji, Imokawa, Genji

Journal:

Laboratory Investigation

Year:

2003

Language:

english

File:

PDF, 3.38 MB

english, 2003

17

Technetium-99m tetrofosmin uptake in lung cancer: Comparison with thallium-201

Ichiro Matsunari, Seigo Kinuya, Takahiro Nishikawa, Munetaka Matoba, Kazuhiro Murakita, Manabu Ohguchi, Kenji Ichiyanagi, Junichi Taki, Norihisa Tonami, Kinichi Hisada

Journal:

Annals of Nuclear Medicine

Year:

1996

Language:

english

File:

PDF, 669 KB

english, 1996

18

Ethanolic extracts of Brazilian red propolis promote adipocyte differentiation through PPARγ activation

Akio Iio, Kenji Ohguchi, Hiroyasu Inoue, Hiroe Maruyama, Yoko Araki, Yoshinori Nozawa, Masafumi Ito

Journal:

Year:

2010

Language:

english

File:

PDF, 726 KB

english, 2010

19

Ethanolic extracts of Brazilian red propolis increase ABCA1 expression and promote cholesterol efflux from THP-1 macrophages

Akio Iio, Kenji Ohguchi, Hiroe Maruyama, Shigemi Tazawa, Yoko Araki, Kenji Ichihara, Yoshinori Nozawa, Masafumi Ito

Journal:

Year:

2012

Language:

english

File:

PDF, 435 KB

english, 2012

20

Inhibition of experimental bone resorption and osteoclast formation and survival by 2-aminoethanesulphonic acid

Masanori Koide, Nobuo Okahashi, Rumi Tanaka, Keiko Kazuno, Ken-ichiro Shibasaki, Yoji Yamazaki, Kenji Kaneko, Nobuo Ueda, Masahiro Ohguchi, Yuichi Ishihara, Toshihide Noguchi, Tatsuji Nishihara

Journal:

Archives of Oral Biology

Year:

1999

Language:

english

File:

PDF, 195 KB

english, 1999

21

Effects of local anesthetics on phospholipase D activity in differentiated human promyelocytic leukemic HL60 cells

Zhiming Tan, Shuji Dohi, Kenji Ohguchi, Shigeru Nakashima, Yoshiko Banno, Yoshitaka Ono, Yoshinori Nozawa

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 431 KB

english, 1999

22

The Role of Activin Type I Receptors in Activin A-Induced Growth Arrest and Apoptosis in Mouse B-Cell Hybridoma Cells

Osamu Hashimoto, Kenji Yamato, Takeyoshi Koseki, Masahiro Ohguchi, Akira Ishisaki, Hiroki Shoji, Takanori Nakamura, Yoshihiro Hayashi, Hiromu Sugino, Tatsuji Nishihara

Journal:

Cellular Signalling

Year:

1998

Language:

english

File:

PDF, 437 KB

english, 1998

23

Isolation of chemical constituents from Enicosanthum cupulare (King) Airy-Shaw

Nozawa, Yoshinori, Koketsu, Mamoru, Fujita, Satoshi, Ninomiya, Masayuki, Efdi, Mai, Ohguchi, Kenji

Journal:

Natural Product Research

Year:

2010

Language:

english

File:

PDF, 196 KB

english, 2010

24

Differential mRNA Expression of Phospholipase D (PLD) Isozymes during cAMP-Induced Differentiation in C6 Glioma Cells

Shin-ichi Yoshimura, Shigeru Nakashima, Kenji Ohguchi, Hideki Sakai, Jun Shinoda, Noboru Sakai, Yoshinori Nozawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 261 KB

english, 1996

25

Increase in Bcl-2 Level Promoted by CD40 Ligation Correlates with Inhibition of B Cell Apoptosis Induced by Vacuolar Type H+-ATPase Inhibitor

Sumio Akifusa, Masahiro Ohguchi, Takeyoshi Koseki, Kazuhiko Nara, Ichiro Semba, Kenji Yamato, Nobuo Okahashi, Ramon Merino, Gabriel Núñez, Nobuhiro Hanada, Tadamichi Takehara, Tatsuji Nishihara

Journal:

Experimental Cell Research

Year:

1998

Language:

english

File:

PDF, 453 KB

english, 1998

26

Sphingosine kinase 1 is involved in dibutyryl cyclic AMP-induced granulocytic differentiation through the upregulation of extracellular signal-regulated kinase, but not p38 MAP kinase, in HL60 cells

Masahiro Koda, Takashi Murate, Shulin Wang, Kenji Ohguchi, Sayaka Sobue, Mika Ikeda, Keiko Tamiya-Koizumi, Yasuyuki Igarashi, Yoshinori Nozawa, Yoshiko Banno

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2005

Language:

english

File:

PDF, 589 KB

english, 2005

27

Involvement of phospholipase D1 in collagen type I production of human dermal fibroblasts

Kenji Ohguchi, Yoshiko Banno, Yukihiro Akao, Yoshinori Nozawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

28

Tyrosine phosphorylation of 100–115 kDa proteins by phosphatidic acid generated via phospholipase D activation in HL60 granulocytes

Kenji Ohguchi, Takeshi Kasai, Yoshinori Nozawa

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1997

Language:

english

File:

PDF, 265 KB

english, 1997

29

Increased mRNA expression of phospholipase D (PLD) isozymes during granulocytic differentiation of HL60 cells

Shigeru Nakashima, Kenji Ohguchi, Michael A Frohman, Yoshinori Nozawa

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1998

Language:

english

File:

PDF, 276 KB

english, 1998

30

Effects of hydroxystilbene derivatives on tyrosinase activity

Kenji Ohguchi, Toshiyuki Tanaka, Tadashi Kido, Kimiye Baba, Munekazu Iinuma, Kenji Matsumoto, Yukihiro Akao, Yoshinori Nozawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 95 KB

english, 2003

31

Differential expression of protein kinase C isozymes and small GTP-bincling proteins during HL60 cell differentiation by retinoic acid and cyclic AMP: Relation with phospholipase D (PLD) activation

Shigeru Nakashima, Yoshihiko Iwasaki, Toshihiro Mizutani, Kenji Ohguchi, Koh-Ichi Nagata, Yasuo Kitajima, Yoshinori Nozawa

Journal:

Year:

1997

Language:

english

File:

PDF, 1.34 MB

english, 1997

32

Phospholipase D development during differentiation of human promyelocytic leukemic HL60 cells

Kenji Ohguchi, Shigeru Nakashima, Yoshinori Nozawa

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

1999

Language:

english

File:

PDF, 283 KB

english, 1999

33

Induction of Apoptosis by Xanthones from Mangosteen in Human Leukemia Cell Lines

Matsumoto, Kenji, Akao, Yukihiro, Kobayashi, Emi, Ohguchi, Kenji, Ito, Tetsuro, Tanaka, Toshiyuki, Iinuma, Munekazu, Nozawa, Yoshinori

Journal:

Journal of Natural Products

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

34

Aberrant distribution patterns of corneodesmosomal components of tape-stripped corneocytes in atopic dermatitis and related skin conditions (ichthyosis vulgaris, Netherton syndrome and peeling skin syndrome type B)

Igawa, Satomi, Kishibe, Mari, Honma, Masaru, Murakami, Masamoto, Mizuno, Yuki, Suga, Yasushi, Seishima, Mariko, Ohguchi, Yuka, Akiyama, Masashi, Hirose, Kenji, Ishida-Yamamoto, Akemi, Iizuka, Hajime

Journal:

Journal of Dermatological Science

Year:

2013

Language:

english

File:

PDF, 2.88 MB

english, 2013

35

Hesperetin Upregulates ABCA1 Expression and Promotes Cholesterol Efflux from THP-1 Macrophages

Iio, Akio, Ohguchi, Kenji, Iinuma, Munekazu, Nozawa, Yoshinori, Ito, Masafumi

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 371 KB

english, 2012

36

Inhibitory Effects of Whisky Congeners on IgE-Mediated Degranulation in Rat Basophilic Leukemia RBL-2H3 Cells and Passive Cutaneous Anaphylaxis Reaction in Mice

Itoh, Tomohiro, Tsukane, Mariko, Koike, Minako, Nakamura, Chizu, Ohguchi, Kenji, Ito, Masafumi, Akao, Yukihiro, Koshimizu, Seiichi, Nozawa, Yoshinori, Wakimoto, Toshiyuki, Nukaya, Haruo, Suwa, Yoshihi

Journal:

Journal of Agricultural and Food Chemistry

Year:

2010

Language:

english

File:

PDF, 3.91 MB

english, 2010

37

Resveratrol Oligomers from Vatica albiramis

Abe, Naohito, Ito, Tetsuro, Ohguchi, Kenji, Nasu, Minori, Masuda, Yuichi, Oyama, Masayoshi, Nozawa, Yoshinori, Ito, Masafumi, Iinuma, Munekazu

Journal:

Journal of Natural Products

Year:

2010

Language:

english

File:

PDF, 976 KB

english, 2010

38

Vaticanol C-Induced Cell Death Is Associated with Inhibition of Pro-Survival Signaling in HL60 Human Leukemia Cell Line

OHGUCHI, Kenji, AKAO, Yukihiro, MATSUMOTO, Kenji, TANAKA, Toshiyuki, ITO, Tetsuro, IINUMA, Munekazu, NOZAWA, Yoshinori

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2005

Language:

english

File:

PDF, 175 KB

english, 2005

39

Inhibitory Effects of Whisky Congeners on Melanogenesis in Mouse B16 Melanoma Cells

OHGUCHI, Kenji, KOIKE, Minako, SUWA, Yoshihide, KOSHIMIZU, Seiichi, MIZUTANI, Yuki, NOZAWA, Yoshinori, AKAO, Yukihiro

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

40

Inhibitory Effects of Resveratrol Derivatives from Dipterocarpaceae Plants on Tyrosinase Activity

OHGUCHI, Kenji, TANAKA, Toshiyuki, ITO, Tetsuro, IINUMA, Munekazu, MATSUMOTO, Kenji, AKAO, Yukihiro, NOZAWA, Yoshinori

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

41

Stimulation of Melanogenesis by the Citrus Flavonoid Naringenin in Mouse B16 Melanoma Cells

OHGUCHI, Kenji, AKAO, Yukihiro, NOZAWA, Yoshinori

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2006

Language:

english

File:

PDF, 128 KB

english, 2006

42

Gnetol as a Potent Tyrosinase Inhibitor from Genus Gnetum

OHGUCHI, Kenji, TANAKA, Toshiyuki, ILIYA, Ibrahim, ITO, Tetsuro, IINUMA, Munekazu, MATSUMOTO, Kenji, AKAO, Yukihiro, NOZAWA, Yoshinori

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2003

Language:

english

File:

PDF, 128 KB

english, 2003

43

Effects of Theaflavins on Melanin Biosynthesis in Mouse B16 Melanoma Cells

YAMAOKA, Yuriko, OHGUCHI, Kenji, ITOH, Tomohiro, NOZAWA, Yoshinori, AKAO, Yukihiro

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 157 KB

english, 2009

44

Activin A Regulates the Production of Mature Interleukin-1/3 and Interleukin-1 Receptor Antagonist in Human Monocytic Cells

OHGUCHI, MASAHIRO, YAMATO, KENJI, ISHIHARA, YUICHI, KOIDE, MASANORI, UEDA, NOBUO, OKAHASHI, NOBUO, NOGUCHI, TOSHIHIDE, KIZAKI, MASAHIRO, IKEDA, YASUO, SUGINO, HIROMU, NISIHARA, TATSUJI

Journal:

Journal of Interferon & Cytokine Research

Year:

1998

Language:

english

File:

PDF, 2.82 MB

english, 1998

45

Activin A Induction of Cell-Cycle Arrest Involves Modulation of Cyclin D2 and p21 CIP1/WAF1 in Plasmacytic Cells

Yamato, Kenji, Koseki, Takeyoshi, Ohguchi, Masahiro, Kizaki, Masahiro, Ikeda, Yasuo, Nishihara, Tatsuji

Journal:

Molecular Endocrinology

Year:

1997

Language:

english

File:

PDF, 5.67 MB

english, 1997

46

Molecular Mechanism of Vapor-Liquid Nucleation

Ohguchi, Koji, Yasuoka, Kenji, Matsumoto, Mitsuhiro

Journal:

Progress of Theoretical Physics Supplement

Year:

2000

Language:

english

File:

PDF, 66 KB

english, 2000

47

Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphoinositide 3-kinase or Akt, in Chinese hamster ovary cells

BANNO, Yoshiko, TAKUWA, Yoh, YAMADA, Momoko, TAKUWA, Noriko, OHGUCHI, Kenji, HARA, Akira, NOZAWA, Yoshinori

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 323 KB

english, 2003

48

Local Anesthetics Inhibit Muscarinic Receptor-mediated Activation of Extracellular Signal-regulated Kinases in Rat Pheochromocytoma PC12 Cells

Tan, Zhiming, Dohi, Shuji, Ohguchi, Kenji, Nakashima, Shigeru, Nozawa, Yoshinori

Journal:

Year:

1999

Language:

english

File:

PDF, 2.65 MB

english, 1999

49

The Biosynthetic Pathway of ( Z )-11-Hexadecenal, the Sex Pheromone Component of the Rice Stem Borer, Chilo sappressalis W ALKER (Lepidoptera: Pyralidae)

Arai, Koshi, Ando, Tetsu, Tatsuki, Sadahiro, Usui, Kenji, Ohguchi, Yoshiko, Kurihara, Matsuo, Fukami, Junichi, Takahashi, Nobutaka

Journal:

Agricultural and Biological Chemistry

Year:

1984

Language:

english

File:

PDF, 607 KB

english, 1984

50

Cytotoxic Benzophenone Derivatives from Garcinia Species Display a Strong Apoptosis-Inducing Effect against Human Leukemia Cell Lines

Matsumoto, Kenji, Akao, Yukihiro, Kobayashi, Emi, Ito, Tetsuro, Ohguchi, Kenji, Tanaka, Toshiyuki, Iinuma, Munekazu, Nozawa, Yoshinori

Journal:

Biological & Pharmaceutical Bulletin

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

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